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3 It is a potent free radical scavenger that also activates several cell signaling pathways associated with the production of new mitochondria and the regulation of cellular energy metabolism.* 3,4 PQQ has been shown to counteract toxin- and free radical-induced neurodegeneration and to enhance the synthesis of nerve growth factor.* 3,5 These biological properties are especially important for cells with high energy demands, such as those found in the heart and brain.* 3,5,6 Supplementing the diet with PQQ may therefore support heart health and promote normal cognitive function as we age.* 7-9 To illustrate, in a randomized, double-blind, placebo-controlled clinical study, healthy older individuals (average age 70 y) received 20 mg PQQ or placebo for 12 weeks

Preliminary data suggest that Epithalon may influence tumor development and radiation sensitivity, though further research is needed

However, their effectiveness may be limited due to poor absorption rates

For instance, the number of eCQMs/MIPS CQMs in the APP Plus quality measure set will increase from four in performance year 2025 to five in performance year 2026

[DOI] [PubMed] [Google Scholar] 398.Yamaguchi T